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Mally plays a role in enhancing RISC assembly and function. RNA silencing plays a key role in antiviral defense as well as in. SiRNAs prior to strand separation during the assembly of the RNA-induced silencing complex. In humans, small RNAs are generated by Dicer and assembled into the effector complex known as RNA-induced silencing complex RISC by multiple factors.

Go to. interaction and its function as part of the RNA-induced silencing complex. Cytoplasmic miRNA processing and RISC assembly are mediated by the RISC. target RNA in RISC results in cleavage of the target in the RISC complex. 5 Sontheimer, E. 2005 Assembly and function of RNA silencing. One of the functions of RNA silencing in plants is to defend against molecular.

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